Transposition of the Great Arteries

Overview

In transposition of the great arteries, the aorta arises from the right ventricle and the pulmonary artery from the left ventricle.

This creates parallel circulations and requires adequate mixing for survival.

Clinical Features

Severe cyanosis often develops shortly after birth and may be accompanied by respiratory distress or circulatory instability.

Investigation

Echocardiography confirms the arterial relationships and associated defects.

Management

Initial stabilization aims to maintain adequate mixing, often with prostaglandin therapy when ductal patency is important.

Definitive repair commonly involves arterial switch surgery.

Clinical Pearls