Overview
Deep vein thrombosis is formation of a thrombus within the deep venous system, most commonly affecting the lower limbs.
Risk reflects venous stasis, endothelial injury, and hypercoagulability.
Risk Factors
Major risk factors include surgery, immobility, malignancy, pregnancy, estrogen exposure, previous VTE, and inherited or acquired thrombophilia.
Clinical Features
Unilateral leg swelling, pain, warmth, and tenderness may occur, although DVT can be clinically silent.
Investigation & Management
Diagnosis commonly integrates clinical probability with D-dimer testing and compression ultrasonography when appropriate.
Anticoagulation is the mainstay of treatment unless contraindicated.
Clinical Pearls
The most important complication of DVT is pulmonary embolism.
END OF REVIEW
Test your knowledge →